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The success of Darwinism was accompanied by a decline in scientific integrity. ... To establish the continuity required by the theory, historical arguments are invoked even though historical evidence is lacking. Thus are engendered those fragile towers of hypotheses based on hypotheses, where fact and fiction intermingle in an inextricable confusion ... where deficiencies of the data were patched up with hypotheses, and the reader is left with the feeling that if the data do not support the theory they really ought to. | |||||||||||||||
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Berkeley has a new website for educators and students named Understanding Evolution. For students, it presents topics on (1) Nature of Science, (2) Evolution 101, (3) Evidence, (4) Relevance of Evolution, (5) Misconceptions, and (6) History of Evolutionary Thought. For teachers, there is additional material on (6) Teaching Evolution, (7) Overcoming Roadblocks, (8) Potential Pitfalls, (9) Readings and Resources. This website is nicely designed and easy to use. It was probably written in response to what Darwin Party defenders like Eugenie Scott lamented about the anti-evolution websites that some teachers are using (see 02/27/2004 headline). The typical arguments and just-so stories are all here, simplified and easily digested without much thought, along with preventive medicine to anesthetize uncooperative students. Some of the answers are really lame (see origin of life, for instance; it sidesteps the issue, tells big lies with glittering generalities and illustrates it with cartoon humor). This website wont teach students much about evolution, but it could provide a good practice pad for baloney detecting.We Dont Know How We Know that Genes Make Minds 02/29/2004 If the mind can be explained from the workings of the brain, and the brain develops by direction from our genes, Anthony Monaco (Oxford) writes, then presumably the mind can be explained from our genetic make-up. But how can only 30,000 genes make a brain with billions of neurons and encode the particular aspects of cognition that make us human? This question opens his book review of The Birth of the Mind: How a Tiny Number of Genes Creates the Complexities of Human Thought by Gary Marcus (Basic Books, 2004) in the Feb. 19 issue of Nature.1 Monaco describes the books proposed answers to two paradoxes: (1) how a small number of genes codes for millions of neurons, and (2) how the brain can code for flexibility: How does the brain of a newborn, with its complex structures and connections, have the plasticity to enable it to respond to environmental influences as it develops further? He seems to agree with the view of author Gary Marcus, a cognitive psychologist, that the brain is built by genes in a self-organized way before being reorganized and shaped by experience and the environment. It is not a battle where one side wins, but a vital interaction. But how do we get from genes to mind, to cognition, thought and reason? Having clarified [sic] these two paradoxes using our current knowledge of genetics and neuroscience, can we explain how genes make minds? The story [sic] is only beginning. This book shows that genes build brains and that brains are designed to be flexible and to learn, but the jump from genes to the mind is an indirect one. The question cannot yet be answered, and it is not entirely clear where the answer will come from.Cognitive psychologists and neurologists have some clues, aided by real-time imaging techniques, but Monaco warns that The path ahead to integrate these disciplines to gain a fuller understanding is optimistically vague.... He warns readers about the sheer complexity of the science. 1Anthony P. Monaco, A recipe for the mind, Nature 427, 681 (19 February 2004); doi:10.1038/427681b. A naturalistic explanation for the mind, soul and spirit does not seem to be forthcoming, does it? (By explanation we do not mean a just-so story; those are always in plentiful supply.)Was There a Single Common Ancestor for All Life? 02/29/2004 Lucy (the alleged human ancestor) had a distant ancestor named LUCA. Thats the assumption of many evolutionary biologists. LUCA, the Last Universal Common Ancestor, is the mother of us all: the bird and the worm, the bee and the flower, the man and his dog. In the Darwinian creation story, sex had not yet evolved, so there was no Adam or Eve or Tree of Life in a garden, but instead, a single, unicellular, primitive ancestor at the root of the Darwinian tree of life (see 08/11/2003, 06/13/2003, and 11/06/2002 headlines). If LUCA is long gone in an unmarked grave, how do we know she (or it) existed? That is the subject of a News Feature by John Whitfield in the Feb. 19 issue of Nature.1 As expected, Charles Darwin sets the stage: Probably all of the organic beings which have ever lived on this Earth have descended from some one primordial form, Darwin wrote in his Origin of Species, published in 1859. Darwin had no way to peer that far back in time. But genome sequencing has given researchers hope that they can finally learn something about the ancestor of all life. In 1999, they even gave it a name, LUCA, for the last universal common ancestor.Finding LUCA is easier said than done. Whitfield laments: Yet despite the wealth of genomic data, LUCA has proven elusive. In theory, remnants of the organism from which all life evolved [sic] should [sic] be scattered around modern genomes. But so far, efforts to reconstruct LUCA's genes by building family trees from modern sequences have ended in frustration. Basic questions about LUCAs nature remain unanswered. Did it live in a hot-water environment, such as a hydrothermal vent at the bottom of the ocean, or in cooler conditions at the ocean surface? Was LUCA simple, like a bacterium [sic], or more complex? (Emphasis added in all quotes.)Whitfield is not about to let frustration lead to depression. He thinks there are clues that an answer may be forthcoming. One suggested answer, however, reflects a major change in thinking about what kind of critter LUCA was: From all this work [sic], one of the more surprising theories to emerge may also help to explain why LUCA has been so hard to find. Perhaps it wasnt a single organism at all. Instead, most researchers now believe we should think of LUCA as a pool of genes shared among a host of primitive organisms.Phylogenetic analysis (building trees from diverse genomes) presents serious statistical difficulties (see 07/25/2002 headline). Also, not all evolutionists agree on whether LUCA was a hyperthermophile (a hot water lover) or lived near the cool ocean surface. Furthermore, only 60 universal genes have been found between the major kingdoms too few by a factor of ten or more to code for a free-living organism. For these reasons, a single LUCA at the base of the tree of life is becoming increasingly difficult to accept: According to some evolutionary biologists, the implications for LUCA are strange indeed. If a single LUCA laid the foundations for the modern diversity in membranes, metabolism and so on, it must have had several different versions of many important genes, in addition to the universal 60. Later lineages would each have pruned all but one from this set, giving rise to the current diversity in basic biochemical pathways. The idea that organisms become more complex rather than less as you get closer to the root of the tree of life is impossible to swallow, says [David] Saul [U. of Auckland, NZ]. A single LUCA would have to have had the most bizarre biochemistry imaginable.One top of that is the growing realization that horizontal gene transfer ran rampant among early unicellular organisms. To Carl Woese (U. of Illinois), that prospect is as deadly to evolutionary biology as a fox in a hen house. It would have scrambled the genetic record, rendering LUCA unknowable. That is why Woese proposed the community hypothesis, a world in which genes acted like modules, able to function on their own. Whitfield elaborates: Ultimately, around 3.5 billion years ago [sic], the modern domains of life would have emerged [sic] from the gene-swapping męlée with many of the genes from the last common community riding on their coat-tails. Inheritance and mutation would then have replaced gene transfer as the most important source of biological novelty as cells became more complex and their functions became less interchangeable. This point, says Woese, was the true origin of species, and so he has christened it the darwinian threshold.Interesting in theory, but would it work? Others are not so sure it wouldnt create bigger difficulties. One resulting problem that would have irked Darwin: ...Patrick Forterre of the Paris-Sud University in Orsay and the Pasteur Institute in Paris, ... says the communal LUCA notion doesnt fit with the way evolution works. To think of LUCA in terms of a community is to remove the idea of darwinism from early evolution, he says. Although LUCA undoubtedly swapped genes with its neighbours, Forterre argues that it would also have competed with them and ultimately triumphed through some key innovation [sic].Theres another difficulty with Woeses idea. Mathematicians from the University of Alberta found that a gene-swapping community in a world of competing resources would have been unstable. In other words, they say, the commune would have fallen apart. Woese shrugs off those problems, confident a different mathematical model might be found to work. Whitfield and Woese both remind us, though, that all these difficulties and disagreements ride on top of another, more serious difficulty, even farther back in the hidden past: Of course, finding LUCA would not solve the puzzle of how life began. The idea of a last common community, with a communally sophisticated biochemistry, raises another question: how did all this evolve? This is for someone else to answer, says Woese. We dont understand how to create novelty from scratch — thats a question for biologists of the future. 1John Whitfield, Origins of life: Born in a watery commune, Nature 427, 674 - 676 (19 February 2004); doi:10.1038/427674a. Welcome to the biology of the future. It is called Intelligent Design. It uses well-understood principles of design detection and information theory. It can be summarized, the essence of life is information (see 12/30/2003, 08/21/2003, 06/12/2003, and 12/30/2002 headlines). If the essence of life is information, the essence of information is intelligent design.No Man Is an Island We Are the World 02/28/2004 Myriads of organisms live in and on our bodies, reminds an article in the Feb. 27 issue of Science,1 and theyre not just freeloaders on a hayride. We need them, and they need us. We are not alone, claim the three microbiologist authors, but we get by with a little help from our (little) friends. Is this an uneasy truce between enemies, or a loving relationship between friends, promoting health and happiness? Microbiologists have tended to investigate the nasty germs, but does that focus give a distorted picture? Remarkably, the authors note, we know far less about the thousands of species that make up our intrinsic microbiota than we know about the few dozen microbes that cause disease. We need to start thinking of ourselves as communities, they say: Genomic and evolutionary [sic] analyses show us that we are not the single individuals that we think we are. Instead, we and other complex organisms are composed of an interconnected ecosystem of eukaryotic and prokaryotic cells whose interactions can best be understood in the context of community ecology. (Emphasis added in all quotes.)The authors feel the community is a result of coevolution, but seem somewhat befuddled at the growing realization that many of our beneficial bacteria share mechanisms with the harmful ones. Friend or foe, they ask: The historical emphasis on pathogenic bacteria and their diseases has led to an assumption that genes encoding virulence factors are specific to those relationships. However, several of the cellular and molecular mechanisms that underlie interactions between an animal and its beneficial microbiota are remarkably similar to those first found in pathogens. Svanborg described how molecules that enhance persistence at a site where a given microbe is a member of the normal microbiota can be the very factors that promote disease when these bacteria emigrate to other sites of the body.... Thus, the presence of these genes may indicate the potential for host interactions, which may be pathogenic or benign according to how these genes are regulated or the sensitivity of the tissue in which they are expressed.The Type III secretion systems, for instance, first described as a mechanism by which animal pathogens hijack their hosts cell biology, have been implicated in mutualistic associations between nonpathogenic bacteria and their hosts. The study of these heretofore misunderstood relationships, they say, forms a wide-open frontier with big paradigm shifts ahead: As the depth of host-microbe interactions and the mechanisms underlying them continue to be unraveled, fundamental paradigms of pathogenic microbiology, developmental biology, and immunology will need to be reevaluated. For this reason, a specific recommendation arising from the workshop is that biology be taught in a new way, incorporating our growing knowledge about the importance of beneficial microbial interactions and their evolutionary [sic], ecological, and biochemical impact on both animals and plants. 1Edward Ruby, Brian Henderson, Margaret McFall-Ngai, Microbiology: We Get By with a Little Help from Our (Little) Friends, Science. One of the most frequent and hard-to-answer criticisms of creation science has been the presence of pathogens. Bacteria and viruses, if designed, would seem to be the nefarious products of a malevolent genius rather than of a compassionate Creator. This was one of the main reasons for Darwins slide to agnosticism, from youthful admiration of Paley to middle-aged rejection of Christianity, revelation and purpose in nature. While most people can appreciate the abundant evidences of design in nature, creationists have been hard pressed to explain disease-causing bacteria and viruses.A Weed Is a Nice Plant at the Wrong Party 02/28/2004 How do weeds go wild? That is a question investigated by Science Now on Feb. 20.1 A complex relationship between a plant and its microbial partners may keep it in check. Transplant that species to an unfamiliar territory, and it may go out of control because it no longer has its restraining pathogens, or natural enemies (if that metaphor is useful: see 07/03/2003 headline). Experiments on knapweed have shown two processes at work: Enemies clearly matter, and thats especially true in the old country. When the researchers grew knapweed in French soil, it fared better in soil that had been previously planted with bunchgrass than with knapweed--presumably because the bunchgrass soil had not accumulated knapweed-specific pathogens. But it appears that enemies arent the whole story. Montana soil showed the opposite pattern: Knapweed planted in soil that had grown knapweed did better there than in once-grassy soil, the team reports in the 19 February issue of Nature. They think that invasive knapweed has not only escaped its natural pathogens in Montana but is modifying the soil to its own advantage, perhaps by cultivating helpful mycorrhizal fungi. 1Erik Skogstad, How Weeds Go Wild, Science Now Feb 20, 2004. The article starts with the language of warfare, but is it misleading?Superstar Challenges Theory 02/28/2004It may not make great action footage for nature documentaries, but plants are in constant battle with each other--for space, light, water--and with soil pathogens that threaten to kill or stunt them. Now its becoming clear just how important this subterranean struggle can be. Plants that escape their natural soil-borne enemies, and strike up alliances with friendly microbes, can become aggressive invaders.This Malthusian, dog-eat-dog imagery may be opposite the truth (see 07/04/2003 headline.) If the plants and their soil organisms are in a balance of growth and regulation, that can be a picture a peaceful homeostasis just as much as the regulation that goes on inside a single cell: agonist and antagonist, on-switch and off-switch, accelerator and brake. A new record holder has been found for biggest star: LBV 1806-20 in Sagittarius. According to the NewsNotes entry on p. 20 of the April 2004 issue of Sky and Telescope, the star is up to 3 times hotter than the surface of our sun, and has a diameter 200 times as big. Most interesting is the stars mass, estimated to be 150 solar masses perhaps more. That ought to make stellar theorists sit up and take notice. No star can survive with more than about 100 or 120 solar masses, according to well-established theory. Theories, like Olympic records, are made to be broken. Let facts be true, and every theory a liar.Anthropic Principle Wont Go Away 02/28/2004 The so-called Anthropic Principle is the observation that the universe, whether by accident or design, appears to have been fine-tuned for our existence. Dating back decades, if not centuries, the idea has been alternately criticized and seriously pondered by the worlds greatest cosmologists. During the 1990s the idea was ridiculed to the point that, if you mentioned the a word at an astronomy conference, you risked being pelted with eggs. Now, according to Dan Falk in the March 2004 issue of Sky and Telescope (pp. 42-47), it is undergoing a surprising resurgence. Several astronomers used the a word at a UC Davis conference in March 2003 and left with clean clothes and thoughtful hearers. Falk lists some of the cosmic coincidences that seem designed for our benefit: (1) the strength of gravity, (2) the smoothness of the Big Bang, (3) The masses of subatomic particles, (4) the strength of the strong nuclear force, and (5) the magnitude of the cosmological constant. There are many other parameters, from atomic to planetary to cosmic, that have been cited in the debate. Some of the parameters Falk lists are recent additions, especially #5. He cites Linde claiming that the cosmological constant is just slightly above zero, yet 120 orders of magnitude smaller than expected. If it were much higher, stars and galaxies could not exist. Are the life-favoring values of these physical constants due to luck, or are they evidence for a benevolent Creator? Falk quotes Paul Davies, Andrei Linde, and other advocates and naysayers. Some, like Stephen Weinberg, think it argues for a multiverse (the idea that our universe is the lucky one out of many, perhaps an infinite number of universes). Surprisingly, Falk gives this bizarre interpretation the best press, calling it more or less established as a viable scientific idea if not an immediately testable hypothesis. Others, however, like David Spergel (Princeton) think the A.P. commits intellectual surrender. Perhaps the most telling criticism of the A.P. is by David Gross, a string theorist (UCSB). Falk says that Gross considers it a dangerous explanation, because it plays into the hands of Intelligent Design supporters, who feel that the universe was custom-made for human beings by a benevolent God (Falks paraphrase). In Grosss words, It smells of religion, and like religion, it cant be disproved. Spergel is similarly disdainful: Some people invoke miracles to explain the underlying processes in evolution, and some people invoke the anthropic principle to explain the underlying processes of cosmology. To him, this is intellectual surrender, claiming that things we dont understand are things we will never understand. Here we see the Elephant in the Living Room phenomenon. Design in nature is the elephant, and the cosmologists are the investigators explaining why the elephant is not really there. The elephant, however, continues to make its presence known, denials notwithstanding.How Science Reports the School Controversies Over Darwinism 02/27/2004 In the Feb. 28 issue of Science,1 Constance Holden reports on the battles over Darwinism vs. creationism in schools across the United States. The tone is one of military alarm. Here is the score as Science sees it (emphasis and underlining added in all quotes; brackets ours):
1Constance Holden, CREATIONISM: Georgia Backs Off a Bit, But in Other States Battles Heat Up, Science Volume 303, Number 5662, Issue of 27 Feb 2004, p. 1268. Its always interesting to watch the spin the Darwin Party Defenders put on this issue. This article is not as bad as some, but the imagery is still not subtle. Here are the tricks of their trade:Evolution of Language Debated 02/27/2004 The Feb. 27 issue of Science features the topic of the evolution of language.1 The thousands of words in 10 articles might be summarized by the title of a book review by Andrew Carstairs-McCarthy: Many Perspectives, No Consensus.2 Since there are many perspectives and no consensus, language evolution is one of the subjects Darwinists love. They can brag about how much they dont know and weave tall tales with reckless abandon, like the one in Nature yesterday (see 02/25/2004 headline).Evolution Is Like the Matrix Revolutions 02/27/2004 Matthew L. Albert enjoyed the Matrix movies. In his review in the Feb. 20 issue of Science,1 he thought the movies were parallels of evolutionary biology. The machines keeping the rebels alive are like retroviruses, he thinks: These retroviruses are responsible in part for our evolution, while other retroviruses are attacking us. So, who is in control? The films illustrate the absurdity of this question. We can no more get along without our retroviruses than the rebels can survive without their machines. He did have a complaint, though: Critics may have difficulty looking past the trilogys not-so-subtle biblical references.... Nevertheless, Albert is at work at the movies: I will continue combing pop culture for insights into the natural world. 1Matthew L. Albert, Immunology: Danger in Wonderland, Science Volume 303, Number 5661, Issue of 20 Feb 2004, p. 1141. Get a real job, Matt.Seniors, Pay Attention: Stay Active 02/27/2004 Cardiovascular activity is good for everyone. Seniors can benefit from taking walks, too. A new study shows it can help the elderly keep their attentiveness and improve mental performance. Science News1 reporter Bruce Bower writes: Seniors interested in pumping up their brains and maintaining an attentive edge might consider taking this inexpensive prescription: Go for a walk every 2 or 3 days. Dont sweat it, but make an effort. Limit each walk to between 10 and 45 minutes.One study showed that fitness was correlated with performance on an activity requiring attentiveness. Another study demonstrated improvement in performance after six months of aerobic training. The results from cardiovascular exercise were noticeably better compared to stretching and toning exercise. Benefits include a sharper mind, better outlook on life, and improved neural functioning that can enhance independent living. Its an all-around good investment. Make walking a regular part of your week, if you can. 1Bruce Bower, Neural Aging Walks Tall: Aerobic activity fuels elderly brains, minds, Science News, Week of Feb. 21, 2004; Vol. 165, No. 8. Those legs were made for walking. Use it or lose it makes sense for limbs as well as talents. Not mentioned in the article is the spiritual benefit you will find from taking walks: thankfulness for the beauty of creation. Get out where the trees are; look at the sky, listen to a bird, and breathe in the fresh air. Go with a friend and get the added benefit of quality time with someone you love. Heres a picture to inspire you. (More in our Photo Gallery.)Beagle 2 Still Lost, But Beagle 1 Found 02/27/2004 Explorers have found partial remains of Darwins lost ship, the HMS Beagle, in a swamp near Kent, reports BBC News (see also Science Now). The ill-fated Beagle 2 on Mars, however, may take another 168 years to find. And it has no water to float in; results from the twin Mars Exploration Rovers are inconclusive about the presence of water on the red planet. Lets hope the Charlies boat doesnt become a religious shrine (see 02/13/2004 headline).Antarctic Dinosaurs Found 02/27/2004 Penguinosaurus? Not exactly, but two previously unknown species of dinosaurs were found in different parts of Antarctica recently, according to EurekAlert. Bones of a theropod and a sauropod were found by separate teams. Judd Case, one of the discoverers of the theropod (of which T. Rex and velociraptor are examples), was perplexed by the find: One of the surprising things is that animals with these more primitive [sic] characteristics generally havent survived as long elsewhere as they have in Antarctica. But, for whatever reason, they were still hanging out on the Antarctic continent. Dinosaur finds are always exciting news, but we dont need the storytelling that usually goes with it.Learn to Speak: Toss a Spear 02/25/2004 Human language evolved after our ancestors learned to throw a spear, according to William H. Calvin, in his new book A Brief History of the Mind: From Apes to Intellect and Beyond (Oxford, 2003). Robin Dunbar is not too sure about this, in a book review in the Feb. 26 issue of Nature.1 Although he respects Calvin, he is not convinced of his thesis for the origin of human language: I found the themes of the book, broadly speaking, congenial, and the account well informed and authoritative, as one might expect from a neuroscientist and science popularist of Calvins stature. However, there are aspects of this particular book that I found less satisfying. Calvins insistence on the importance of a gesturally based phase to language evolution does not, I think, make sense. Language is a parsing skill, and, even though parsing is a hierarchical process, it seems to me to be a very different kind of skill from that used in coordinated throwing. Manipulating concepts is not the same kind of activity as manipulating muscle masses. Nor does the timing really work. The evidence [sic], as Calvin himself notes, points to a period about 500,000 years ago [sic] as the likely [sic] timing for the origin of speech, if not full-blown language. But the archaeological record is very clear that real projectile-based hunting did not become widespread until the Upper Palaeolithic revolution, which kicked in around 50,000 years ago [sic] (perhaps a little earlier in Africa). The evolution of speech, then, pre-dates the fine muscle control of aimed throwing by a very wide margin.He also found Calvins look into the future unconvincing. Nevertheless, Dunbar is glad that After a century of neglect, the mind has suddenly become an issue of evolutionary interest once again. 1Robin Dunbar, Could throwing spears have laid the foundations for language acquisition?, Nature 427, 783 (26 February 2004); doi:10.1038/427783a. Dunbar is way too polite with his criticism. Why? Darwin Party members are loathe to call each other stupid. It might provide fodder for those darned creationists.How Darwinians Approach the Golden Rule 02/22/2004 Is nothing sacred? Gretchen Vogel has written a piece on The Evolution of the Golden Rule in the Feb. 20 issue of Science.1 Jesus Christ and most religious teachers have taught the Golden Rule as a moral principle and a sacred duty, but to Darwinians, it must have evolved like everything else. Yet this poses a conundrum, as Vogel states in the subtitle: Humans and other primates have a keen sense of fairness and a tendency to cooperate, even when it does them no discernible good. In a world of competition, fitness and survival, why would animals cooperate, or why would one lay down his life for his friends? Vogel describes competing theories, such as strong reciprocity, game theory, and reciprocal altruism. Studies on monkey fairness, neurological signals, and mathematical modeling have each participated in answering the question, but each of the explanations offered have one thing in common. They assume the Golden Rule is an artifact of an evolutionary process, not a moral absolute. (The article also touches on the evolution of suicide bombings.) 1Gretchen Vogel, Behavioral Evolution: The Evolution of the Golden Rule, Science, Volume 303, Number 5661, Issue of 20 Feb 2004, pp. 1128-1131. If this article doesnt make you mad, it should. It means nothing less than the demise of personal responsibility and the downfall of civilization. If suicide bombing is merely an evolutionary behavior, then it is not morally wrong, just unfortunate for the victims. Pastors and believers everywhere had better wake up and get angry that the ultimate altruism, depicted in The Passion, is being presented by mad scientists as the result of evolution from monkey antics. This is not only disingenuous (see 12/18/2002 headline) and blasphemous to a large segment of the population, but a self-defeating claim. A Golden Rule that evolves is neither golden, nor a rule. Its fools gold. These charlatans use humans as lab rats (see 06/25/2002 headline), but exclude their own intellects as relics of rat behavior. Lets turn the game on them and ask about the The Evolution of Evolutionary Nonsense. Short circuit!SETI Sans ETI So Far 02/20/2004 Theres no din of alien chatter in our neighborhood, writes Richard Kerr in the Feb. 20 issue of Science.1 Early-generation searches for extraterrestrial intelligence are coming up empty-handed, but the SETI community is carrying on, he writes. Search pioneer Frank Drake admits We found nothing in the latest Project Phoenix, a survey of 700 nearby sunlike stars. James Trefil adds, this idea theres a galactic club that we would join as soon as we started ... doesnt look like its panning out. Paul Horowitz is not near ready to quit, though, urged on by the conviction that There's got to be life in the galaxy. Statistically, even with optimistic assumptions, it would not be probable to have found one by now just hopeful. Upcoming searches promise to be quicker and more powerful. But if there are only 10,000 alien civilizations surfing the galactic radio internet, it could take decades to find one. The importance of a positive signal keeps the search going. Until one is found, however, SETI has been termed by Seth Shostak as looking for an uncertain manifestation of a hypothetical presence. 1Richard Kerr, No Din of Alien Chatter in Our Neighborhood, Science Volume 303, Number 5661, Issue of 20 Feb 2004, p. 1133. Without the belief in Darwinian evolution, one wonders how much motivation SETI would have. Would believers in God expect to find life all over the universe trying to contact us? If so, would they work this hard looking? The Darwin Party seems to think a discovery of alien life would disprove the Bible, but is that necessarily true? Why would it not just as clearly indicate creation? What if the aliens tell us they evolved, but are lying? What if they turn out to be storytellers as incorrigible as members of the Darwin Party here on earth?Darwin Propagandist Reveals Too Much 02/20/2004 You cant always tell a chocolate by its coating. Similarly, a positivistic, pro-evolution article might have surprises inside. Billions of years of evolution have produced organisms of stunning diversity, begins Eörs Szathmáry in the Feb. 17 issue of Current Biology,1 with vintage Darwinian confidence. A theoretician at heart, Szathmáry explores the evolutionary transitions not by looking at bones or genes, but by making models of intermediate stages of organisation and the evolutionary transitions between them. Theoretical biology had its Golden Age, he claims, when Fisher, Haldane and Wright founded population genetics in the first half of the twentieth century. As he justifies his conceptual-over-empirical approach, he reveals some large gaps in evolutionary theory. He evidently feels Darwinism provides enough conceptual material in each case to fill in the gaps, but it will be up to the reader to judge his success:
Take evolutionary biology, for example. A few decades after the Golden Age, evolutionary biologists started to tackle (ultimately with considerable success [sic]) questions where the Darwinian answer is far from obvious. Why do we age? Why are there sterile insect castes? At first it does not seem to make much sense to argue that your death or sterility increases your fitness. But evolutionary theory can [sic] provide satisfactory resolutions of these conundrums. In some cases even the question itself cannot be formulated well enough without some modelling: the problem of the evolutionary maintenance of sex is a case in point. Whole sub-disciplines, like evolutionary game theory, have been set up to meet such challenges. The problems become a lot harder when we come to the large-scale dynamics of evolution. Imagine, say, a thousand Earth-like planets with exactly the same initial conditions of planetary development. After one, two, three billion years (and so on), how many of them would still have living creatures? And would they be like the eukaryotes? We have simply no knowledge about the time evolution of this distribution, and ‘educated’ guesses differ widely. Still, when contemplating [sic] lifes origins, the gap between Millers world and the DNA world is discouragingly enormous. How do you get from the primordial soup to the genetic code? The snag is that, in contemporary biological systems, there is a division of labour between nucleic acids and proteins: the former store genetic information and the latter exert function. Genetic information is expressed with the help of proteins, which are encoded by nucleic acids. We seemed to be at an impasse: no genes without proteins and no proteins without genes – the classic ‘chicken and egg’ problem.Szathmáry is not the first, of course, to point out this conundrum, but he quickly suggests that it now seems that the primordial soup [sic] may not have been that important, and that we may not need a genetic code for early life. As support, he refers to the RNA World hypothesis, that one molecule (RNA) might have performed both information-storage and enzymatic functions. How this would obviate the need for a soup of chemicals or a genetic code is not explained.
The chemoton is an abstract model of a minimal biological system comprising three sub-systems: a metabolic cycle producing the materials for all three sub-systems at the expense of nutrients; a replicating template; and a boundary membrane. All three systems are autocatalytic, and the system as a whole can also divide in space within a certain parameter range.Nevertheless, he thinks Gántis modeling is as valid as were Galileos experiments with smooth balls rolling down smooth slopes. Comprehending this analogy is left as an exercise. (For more on requirements for minimal life, see 02/15/2004 headline.)
The simplest [sic] autonomous living systems today are prokaryotes, the results of billions of years [sic] of evolution [sic] . There is just no way that a prokaryote with its genetic code could have self-assembled in the primordial soup. There must have been a long [sic] phase of evolution [sic] by natural selection from the first living entities to bacteria, as Gánti recognized in 1971. But how can one think of these earliest systems? Chemoton theory offers [sic] such a conceptual breakthrough.From here he jumps to trends in synthetic biology, seeming to promise the checks in the mail on the origin of life. 1Eörs Szathmáry, Magazine: From biological analysis to synthetic biology, Current Biology, Vol 14, R145-R146, 17 February 2004. When your opponent is shooting himself in the foot, there is really no need to return fire, but rather to sit back and enjoy the entertainment.How to Get a Genetic Code by Chance 02/19/2004 The Feb. 17 issue of Current Biology1 has a Q&A magazine feature on the genetic code. After dismissing some myths about it being universal, consisting of only 20 amino acids and obligated to only three codons (there are some minor exceptions to these mostly-true principles: see 04/30/2003 headline), the authors tackle the big question: where did it come from? I heard about a ‘frozen accident’…(Emphasis in original.) 1Andre R.O. Cavalcanti and Laura F. Landweber, Magazine: Genetic Code, Current Biology Vol 14, R147, 17 February 2004. They just violated Occams razor. They also violated the rule that three wrongs dont make a right.Early Man Studies: Start Over 02/19/2004 Anthropologist Leslea J. Hlusko (U. of Illinois) had some stern advice for her paleoanthropologist colleagues in PNAS1 recently. Noting that Competing interpretations of human origins and evolution have recently proliferated despite the accelerated pace of fossil discovery, she thinks an approach is needed that integrates genetics and development with the search for bones. She takes issue with three presumptions that can confuse and mislead the interpretation of fossils:
1Leslea J. Hlusko, Integrating the genotype and phenotype in hominid paleontology, Proceedings of the National Academy of Sciences USA, March 2, 2004, vol. 101, no. 9, pp. 2653–2657. Published online before print. This is a revealing article that basically says, everything you know is wrong, and we hope we can figure out the truth some day by starting over. Like so often reported here, it is more admission of ignorance and promises of futureware. Quote-hunters might find a bonanza in this article.Respect the Conch Shell 02/19/2004 Engineers and materials scientists seem to never run out of examples in nature that should fill us with awe. In the Feb. 19 issue of Nature,1 Rosamund Daw brings our attention to the construction ability of the conch shell: Giant conches are seldom treated with the respect they deserve. Their impressive shells are prized as holiday souvenirs, but size and aesthetics are only half the story. At the microscopic scale, they are one of natures greatest engineering masterpieces: a stunningly intricate hierarchical architecture of inorganic crystals, interwoven with organic molecules. (Emphasis added.)Recent experiments have shed light on the ways these marine organisms build and repair their shells. An organic layer is deposited, providing a base on which fine crystals of aragonite form perpendicular to the organic layer. Then a three-layered, cross-lamellar structure grows a few millimeters thick, forming the body of the shell. The result is a strong, exceedingly fine structure, often decorated with streaks or spots of intricate colors, with bumps and horns and geometric spiral shapes. Broken shell? No problem. When experimenters drilled a hole into the shells of living conches, a new organic layer was formed within 24 hours, upon which new aragonite crystals grew to begin the repair process. Theres still much to learn about the complex process of shell formation, Daw says. It remains to be discovered how the interplay of organic and inorganic components is controlled at the molecular level, in conch shells as well as in other mineralized structures. 1Rosamund Daw, Materials Science: Give a shell a break, Nature 427, 691 (19 February 2004); doi:10.1038/427691a. This could be a teachable moment on your familys next trip to the beach. Tell the kids that this construction project the conch performs is the envy of materials scientists. Teach them that complex processes that build things do not just happen. DNA, genes, enzymes, signalling, feedback and quality control all contribute to the work of art that is a seashell.Irreducible Complexity: Can It Be Explained Away? 02/18/2004 When Sharon Begley, writing in the Wall Street Journal Feb. 13, criticized the intelligent design movement (see reprint on Access Research Network), Michael Behe answered with a pointed reply five days later. Begley particularly singled out the concept of irreducible complexity. Behes reply, defending the validity of irreducible complexity (a term he coined in his 1996 book Darwins Black Box as evidence for intelligent design), can be read on the Discovery Institute website. Another article on intelligent design was printed on SpaceDaily.com. In it, Ronald Numbers, a historian of the controversy over Darwinism, thinks that inroads of intelligent design into the classroom might be a good thing, but doubts the scientific societies will ever accept it, because it would involve a major change in the way science is done: The intelligent design people are saying that if the goal of science is to discover the truth, why should scientists, a priori, reject the theory of intelligent design? Charlie Darwin said a fair evaluation of any question can only be made when both sides are heard. Strange that many of his disciples dont want you to hear the opposition. They think their sound bites tell you all you need to know about any controversy surrounding their idol. Numbers is an apostate Christian who accepts many of the Darwinian myths, but thankfully he seems to not be as viciously dogmatic as the rest of the Darwin Party against intelligent design. It is notable that SpaceDaily.com printed this partially open-minded article. Too bad they didnt allow a qualified ID spokesman to make the case.Birds Are Memory Champs 02/17/2004 We humans lose our keys and often cant remember the location of half a dozen identical items. Maybe it takes a bird brain to find the car keys, teases Susan Milius in the cover story of the Feb. 14 issue of Science News.1 Ornithologists have been intrigued with how birds remember where they stash their food. One champ is Clarks nutcracker, a noisy denizen of western national parks observed and named by the Lewis and Clark expedition. In a year, each bird buries 22,000 to 33,000 seeds and manages to find two thirds of them 13 months later. Chickadees and scrub jays are pretty good at this game, too. Experiments have demonstrated that bird memories are flexible and can even do time travel into the future. How could such good memories evolve? The only going theory seems to be that tough times select for better memories. As evidence, researchers found that Alaskan chickadees outperformed Coloradoans in a seed storage and retrieval contest. Not all ornithologists are convinced of this theory, however, since the two species differ in many other respects. To resolve the question of whether tough times have contributed to the evolution of catching wizardry is currently difficult, says [Nicola] Clayton [Cambridge]. More experiments will be required, but Milius concludes, What started out as a fidgety search for the operating rules of feathered robots has turned into studies of how thinking works. 1Susan Milius, Whered I Put That? Science News, Vol. 165, No. 7, Feb. 14, 2004, p. 103. The claim that tough times create design is like the Phoenix myth, that a living bird arises from the flames of catastrophe. No. Fire burns, and stress kills. Making stress a creative genius is no explanation at all, yet it remains a favorite plot in Darwin stories. Didnt an asteroid blast give rise to the zoo of complex and diverse mammals, according to the going myth? We can enjoy the marvels of birds without the insipid, useless, wasteful, distracting, unsupportable, pseudoscientific bad habit of trying to find evolutionary origins for everything. Remember that.DNA Is a Code Operated by Another Code 02/17/2004 The discovery in the 1950s that DNA stored a coded language was amazing, but recently a new level of complexity has come to the awareness of biochemists. Apparently, another code determines which DNA genes will be opened for expression and which should be suppressed. The Feb. 14 issue of Science News1 describes the history of the discovery of the so-called histone code. These are patterns of tails attached to the histones around which DNA is tightly wrapped. Within the last eight years, scientists have been discovering that the histones do not merely spool the DNA, they regulate which genes get expressed. The pattern of acetylation and methylation on the histone tails appears to form a code that is heritable through cell divisions. Compared to the well-known DNA genetic code, A histone code may be much more complex, writes John Travis. Shelley Berger (Wistar Institute) exclaimed, There are all kinds of sites [on histone tails] that can be modified. The possibilities for a code are quite enormous. Its not going to be a simple code. After summarizing the literature, Travis concluded, With such designer histones, it seems that researchers are on their way to having in their hands all the words of the histone code. But, it may still be a stiff challenge to figure out what those words mean. For a previous story on the histone code, see 11/04/2002 headline, Cell Memory Borders on the Miraculous. 1John Travis, Code Breakers: Scientists tease out the secrets of proteins that DNA wraps around, Science News, Vol. 165, No. 7, Feb. 14, 2004, p. 106. Evolutionary biologists had their hands full explaining the origin of the DNA-protein language, and now this. As usual, there is no description in the article about how this code might have emerged through an evolutionary process. There is only the following quip, that not only fails to explain the codes origin, it adds another problem: apparently the code has not evolved at all: From species to species, he [C. David Allis, U. of Virginia] notes, these tails are nearly identical, implying that they are important to the cell. Nature has held these things constant for a reason, says Allis. Certainly. Give me a working histone code in the beginning, or give me death.Scientists Probe Differences Between Living and Nonliving Chemicals 02/15/2004 All life forms are composed of molecules that are not themselves alive. But in what ways do living and nonliving matter differ? How could a primitive life form arise from a collection of nonliving molecules? Any article beginning with questions like that is bound to be interesting. Thats how Rasmussen et al. tantalized readers of Science1 on Feb. 13 as they described two recent international workshops discussing the origin of life and artificial life. The workshops, one at Los Alamos and one in Germany, focused on two overlapping questions: (1) How did life originate? and (2) Will scientists ever be able to create life? Regarding the latter, some are taking the top-down approach, taking the smallest known living organism and trying to tweak it, and others are taking a bottom-up approach, trying to build a self-replicating cell from scratch. The bottom-up approach is general and more challenging, but holds more promise, they think, for understanding ways in which life might have originated on its own. Recognizing that the definition of life is notoriously controversial, the authors sought middle ground in their definition: there is general agreement that a localized molecular assemblage should be considered alive if it continually regenerates itself, replicates itself, and is capable of evolving [sic, emphasis added in all quotes]. (For another view, see 12/30/2002 headline.) Those seeking to produce a cell matching those criteria have generally recognized three requirements that would have had to be met: genetic information, metabolism, and containment: Regeneration and replication involve transforming molecules and energy from the environment into cellular aggregations, and evolution requires heritable variation in cellular processes. The current consensus is that the simplest way to achieve these characteristics is to house informational polymers (such as DNA and RNA) and a metabolic system that chemically regulates and regenerates cellular components within a physical container (such as a lipid vesicle).The scientists have developed models of how these three requirements might be met, and have partially achieved some of them separately One proposal would make use of a simpler polymer than DNA/RNA, called PNA. According to the model, light energy might synthesize lipids (for the container) and PNA, with the PNA... ...acting as both an information molecule and as an electron-relay chain. This is the first explicit proposal that integrates genetics, metabolism, and containment in one chemical system. Metabolism in this system has been shown to produce lipids, but experimental realization of the rest of the integrated system has not yet been achieved.Harold Morowitz (George Mason Univ.), long interested in the requirements for a minimal living system (see online reference at this site), helped clarify the divide between living and nonliving matter. Morowitz and three colleagues gave presentations at the workshops: They described how nonliving chemical reactions, driven by thermodynamics, explore the state of space in an ergodical fashion, and thus tend to conduct a random exhaustive search of all possibilities; in contrast, living systems explore a combinatorially large space of possibilities through an evolutionary process [sic]. This echoed a central workshop theme: how and when information becomes a dominant factor in the evolution [sic] of life, that is, how and when selection plays a greater role than thermodynamics in the observed distribution of phenotypes.This opened up a number of proposals by Morowitz and others:
(i) What is the boundary between physical and biological phenomena? (ii) What are key hurdles to integrating genes and energetics within a container? (iii) How can theory and simulation better inform artificial cell experiment? (iv) What are the most likely early technological applications of artificial cell research?In addition, work on artificially-created nanobots, including some that could repair and replicate themselves, require cautious courage, because creating such entities would literally form the basis of a living technology possessing powerful capabilities and raising important social and ethical implications. The authors noted that everyone at the workshops was confident that useful artificial cells will eventually be created, but there was no consensus about when. 1Rasmussen, Chen, Deamer, Krakauer, Packard, Stadler, and Bedau, EVOLUTION: Transitions from Nonliving to Living Matter, Science Volume 303, Number 5660, Issue of 13 Feb 2004, pp. 963-965, 10.1126/science.1093669. We almost titled this entry Mad Scientists Threaten World With Destruction! but didnt want to scare the adults. Here you have it, folks: Frankenscience alive and well in the labs that gave us atomic bombs. Our next fear may be artificial cells too small to see that will wreak havoc on us, brought about by some out-of-control prize seeker with courage but not enough caution. |